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    ²Î¿¼ÎÄÏ×
    1 ÖÜËÉ.¹û½º×ÛºÏÂÛÊö.°²»Õʦרѧ±¨,1995(4)¡Ã76~80.
    2 ÕÅѧ½Ü,¹ù¿Æ,ËÕÑÞÁá.¹û½ºÑо¿Ð½øÕ¹.ÖйúʳƷѧ±¨,2010,10(1)¡Ã 167~174.
    3 ½¹ÔÆÅô,Ðìΰ,ÖìÐãÁé,µÈ.µÍõ¥¹û½ºµÄÖƱ¸¡¢Ó¦ÓúÍÑо¿½øÕ¹.ËÄ´¨¹¤ÒµÑ§ÔºÑ§±¨,2004(4)¡Ã57~58.
    4 Ellen G M, Nigel J B, Keith W W, et al. Pectin-an emerging new bioactive food polysaccharide. Trends Food Sci Tech, 2012, 24(2)¡Ã21~37.
    5 ÚùÏþæº,ÕÅ°®Õä,³Â½¨¹ú,µÈ.µÍ·Ö×Ó¸ÌéÙ¹û½º·Û¶ÔÌÇÄò²¡Ð¡ÊóѪÌÇѪ֬µÄµ÷Àí×÷ÓÃ.ÖйúÈ«¿Æҽѧ,2006,9(20)¡Ã1685~1686.
    6 ÕÅÎIJ©,Áõ³¤ÖÒ,¸ßÁÖ.¸ÄÐÔ¸ÌéÙ¹û½ºµÄÖƱ¸¡¢±íÕ÷¼°¿¹°©»îÐÔ.¸ßµÈѧУ»¯Ñ§Ñ§±¨,2010(5)¡Ã964~969.
    7 Íô·å,Áõº£Ó¥.µÍ·Ö×Ó¸ÌéÙ¹û½ºÔÚÖ×ÁöÖÎÁÆÖеÄÑо¿½øÕ¹.¹ã¶«Ò½Ñ§,2011,32(20)¡Ã2747~2749.
    8 Takayuki T, Kotaro S, Masshiro Y, et al. Inhibition of metastatic tumor formation in vivo by a bacteriophage display derived galectin-3 tar£­geting peptide. Clin Exp Metastas, 2013, 30(2)¡Ã119~132.
    9 ÕÅÎIJ©. MCP ¶àÌǵÄÖƱ¸¡¢ÆÊÎö¼°Æ俹Ö×Áö»îÐÔµÄÑо¿.Ìì½ò£ºÌì½ò´óѧ²©Ê¿Ñ§Î»ÂÛÎÄ,2006.
    10 ·¶ÓñÓ¨.È˲ιû½º¶Ôϸ°ûǨÒƵÄÓ°Ï켫Æä»úÀíÑо¿.³¤´º£º¶«±±Ê¦·¶´óѧ²©Ê¿Ñ§Î»ÂÛÎÄ,2010.
    11 ÐìºñΡ. µÍ·Ö×Ó¸ÌéÙ¹û½ºÉ±É˽᳦°©Ï¸°ûÀú³ÌÖÐÒªº¦µòÍöÂѰ׵ĻîÐÔ.¹ãÖÝ£º¹ãÖÝҽѧԺ˶ʿѧλÂÛÎÄ,2010.
    12 ÞÉÃçÃç. ¹û½º-ͪÂå·ÒÇ°Ò©µÄºÏ³É¡¢½á³¦°ÐÏòÐÔºÍҩЧѧÑо¿. Î÷°²£ºµÚËľüÒ½´óѧ˶ʿѧλÂÛÎÄ,2005.
    13 Guess B W, Scholz M C, Strum S B, et al. Modified citrus pectin (MCP) increases the prostate-specific antigen doubling time in men with prostate cancer: a phase II pilot study. Prostate Cancer Pro£­static Dis, 2003, 6(4)¡Ã301~304.
    14 Tin W W, Gaia C, Fabio S, et al. Pectin matrix as oral drug de£­livery vehicle for colon cancer treatment. AAPS Pharm Sci Tech, 2011,12(1)¡Ã201~214.
    15 Àî¼Ñ.È˲ιû½º-°¢Ã¹Ëظ´ºÏÎïµÄÖƱ¸ºÍ¿¹Ö×Áö»îÐÔ.³¤´º£º¶«±±Ê¦·¶´óѧ˶ʿѧλÂÛÎÄ,2007.
    16 Tazawa K, Ohkami H, Yamashita I, et al. Anticarcinogenic and/or antimetastatic action of apple pectin in experimental rat colon car£­cinogenesis and on hepatic metastasis rat model. Acs Symposium Series. J An Chem Soc, 1998,701¡Ã96~103.
    17 Victor J M, Nigel J B, Keith W, et al. The bioactivity of modified pectin fragments. J Lunn and J L Buttriss, 2013, 1(1)¡Ã21~37.
    18 Niture S K, Refai L. Plant pectin: A poteintial source for cancer suppression. Am J Pharmac and Toxico, 2013,8(1)¡Ã9~19.
    19 Dongowshi G, Lorenz A. Intestinal steroids in rats are influenced by the structural parameters of pectin. J Nutr Biochem, 2004, 15(4)¡Ã196~205.
    20 Ide T, Horii M, Yamamoto T, et al. Contrasting effects of water - soluble and water insoluble dietary fibers on bile acid conjugation and taurine metabolism in the rat. Lipids, 1990, 25(6)¡Ã335~340.
    21 Vladislav V, Glinsky, Raz A. Modified citrus pectin antimetastatic properties: one bullet, multiple targets. Carbohydrate Res, 2009, 344 (14)¡Ã1788~1791.
    22 Nangia M P, Nakahara S, Hogan V, et al. Galectin-3 in apoptosis, a novel therapeutic target. J Bioenerg Biomembr, 2007, 39(1)¡Ã79~84.
    23 Story J, Lord S. Bile salts: In vitro studies with fibre components.
      
    Progress on Anti-tumor Activity of Pectin
    Li Yinghua1 , Zhu Wei1, 2
    (1. The Fifth people's Hospital of shanghai, Fudan University, shanghai 200240, China;
    2. Industrial Technology Research Institute of Zhejiang University, Hangzhou 310029, China)
    ¡²World Science and Technology/Modernization of Traditional Chinese Medicine and Materia Medica¡³
    Abstract: In this article, we reviewed studies on anti-tumor activity of pectin in recent years through data retrieval. The tumor treatment effect with pectin and interaction among anti-tumor medications were summarized. The analysis was made on the effect of pectin and Galectin-3 in tumor in order to discuss the anti-tumor mechanism of pectin. Finally, the development trend of anti-tumor study of pectin was pointed out to provide references.
    Keywords: Pectin, anti-tumor, activity study, review
     
     
     
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