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Knowledge of Modified Citrus Pectin

1. What is citrus pectin?
       Citrus Pectin is a polysaccharide compound extracted from peels of citrus fruits, such as lemon, orange and grapefruit. It is long-chain carbohydrate with molecular weight of 50-300 thousands Da, degree of esterification is 20-75%.
       Natural citrus pectin is generally used as a food additive, has good gelling, stabilizing, emulsifying, thickening and suspension function.             Pectin is a natural water-soluble dietary fiber without any side effects, plays an important role in health foods.
      Natural pectin cannot be absorbed in the intestine, only plays beneficial role to the digestive system.

2. What is modified citrus pectin?
        Modified citrus pectin (MCP in short) is also known as low molecular weight citrus pectin (LCP in short), is a product of natural citrus pectin after hydrolysis. Its molecular weight is 5000-35000Da, degree of esterification is 2-30%. The role of hydrolysis is to reduce the molecular weight and degree of esterification. MCP is easily absorbed in the intestine and can be into the blood circulation, directly stimulate the body's immune system. Since MCP is rich in galactose monomer, it can produce specific tumor suppression function. MCP can significantly improve appetite, support health cell growth, regulate blood sugar and blood lipid, protect liver health and inhibit tumor metastasis. Thus, MCP can be widely used as ingredient of medicines, functional foods and skin care products.

3. Why MCP has different functions?
        Experiments show that MCP with different technical parameters (such as molecular weight, degree of esterification and different raw materials) has different functions. Gold Kropn has close cooperation in functional tests with agencies like Zhejiang University, Tianjin University, Xinxiang Medical University, etc., selected the best technical indicators. Test results show that MCP has functions such as anti-tumor, skin care, relieve constipation, etc.
 
4. The safety of MCP.
        FAQ and WHO recommended MCP as safe component without daily intake limitation. Gold Kropn uses 100,000 grade GMP workshop and Argentina lemon peel, uses biological enzyme technology to extract MCP, strict control raw materials and production process, does not add any chemical raw materials.
        MCP is a healthy product without side effects. It is beneficial to all kind of people.

5. How do you take MCP?
        It’s better to take MCP before meals. MCP can mix with warm water, also be added to fruit juices, beverages and other foods.
        Tips: MCP can play better function under acidic conditions. You can use blender to mix MCP with fruits you like (see picture below).

6. What is the mechanism of MCP anti-tumor function?
        MCP is easily absorbed by the intestine and enters the blood circulation. It can significantly improve appetite, enhance the sensitiveness to chemotherapy and radiotherapy, and reduce toxic side effects. MCP can compete with tumor-associated protein galectin-3, block tumor cells, prevent nutrient uptake of tumor cells, inhibit aggregation and adhesion to normal cells, reduce tumor cells activity, prevent the formation, development and metastasis of tumor cells.

7. Which tumors are MCP effective at?
        MCP can work with all tumors that have galectin-3 expresses on the surface, and the efficiency is positive related to the expression. According to the patent and references, MCP can work with following 19 cancer, including:
Prostate cancer, renal cancer, Kaposi's sarcoma, chronic leukemia, breast cancer, sarcoma, ovarian cancer, colorectal cancer, throat cancer, lymphoma, melanoma, small intestine cancer, bladder cancer, lung cancer, bronchial cancer, pharyngeal squamous cell carcinoma, gastric cancer, skin cancer, liver cancer, gum fibromas, thyroid cancer, bone cancer.

Following table summarizes some of the test results of MCP effective

rate:

8. Does MCP has any side effects?
        MCP does not kill tumor cells directly but through chelation of galectin-3, prevents tumor cells adhesion and nutrient uptake and does not has any clinical toxic or side effects. Very few patients will have dilute stool and increased frequency, but with no pain, fatigue or other discomfort. The reason is that the individual patient’s gastrointestinal tract is galacturonic acid-sensitive. It’s appropriate to reduce the daily dose, the symptom will disappear one to two weeks, and will not have a negative impact on the body. MCP is a high security functional food.

9. Why can MCP support women health?
      MCP has been shown to support healthy cellular growth and reproduction, repair skin and dilute spots. Its anti-bacteria effect helps to reduce acne. MCP can form a layer of film distribute on the surface of skin, retaining water and moisturize skin. In the meanwhile, MCP can absorb ultraviolet rays, inhibit the formation of melanin and whitening the skin.

6. What is the mechanism of MCP anti-alcohol function?
       MCP has good water solubility, which can form a layer of protective film in the gastrointestinal wall to prevent alcohol absorption. What’s more, it can activate internal anti-alcohol enzyme activity, accelerate the decomposition and metabolism of alcohol, promote liver health.

11. Why can MCP regulate blood sugar and blood lipid?
       MCP can accelerate the conversion and discharge of cholesterol through a variety of mechanisms, delay the intestinal absorption of sugars and lipids, activate sugar metabolism related enzyme activity, promote normal blood sugar and blood lipid, supports kidney health.

12. Why can MCP enhance gastrointestinal tract health?
       MCP has strong water holding characteristic, containing more than 80% water soluble dietary fiber. It can prevent the dryness of stool in the intestine, relieve constipation
，promote gastrointestinal peristalsis and help to maintain healthy digestive system.