Compositions and methods for treating mammals with modified alginates and modified pectins

US6462029 B1

A modified alginate and/or modified pectin composition for preventing and/or treating diseases and/or conditions caused by circulating agents such as poisonous heavy metals, environmental toxins, calcium and cholesterol, is provided. The composition includes a modified alginate having a molecular weight of no more than 40,000 daltons and/or a modified pectin having a molecular weight of no more than 40,000 daltons. The method involves orally or intravenously administering the modified alginate and/or modified pectin composition, alone or with excipients.

Claims

Claim #1

A method of treating or preventing poisoning in a mammal which is caused by circulation in the blood of said mammal of a poison selected from the group consisting of toxic metals, enviromental toxins and mixtures thereof, comprising administering to a marnmal in need of same an effective amount of modified alginate having a molecular weight of no more than 40,000 daltons, and obtained by hydrolysis or enzymatic degradation of alginic acid, in an amount to effectively bind said poison.

Claim #1 Dependents

The method of claim 1, wherein said poisoning is metal poisoning, and said poison is a poisonous heavy metal.

Claim #2 Dependents

The method of claim 2, wherein said heavy metal is selected from the group consisting of aluminum, antimony, beryllium, bismuth, mercury, platinum, thallium, thorium, tin, tungsten, uranium, lead, mercury, cadmium, arsenic, silver, nickel, radioactive metals and mixtures thereof.

Claim #3 Dependents

The method of claim 3, wherein administration of said modified alginate is accompanied by administration of modified pectin having a molecular weight of no more than 40,000 daltons obtained by hydrolysis or enzymatic degradation of pectin.5

The method of claim 1, wherein said modified alginate is administered orally or intravenously.

Claim #5 Dependents

The method of claim 5, wherein said modified alginate is administered orally in an amount of from 5-1,500 mg per kg body weight per day.7

The method of claim 5, wherein said modified alginate is administered intravenously in an amount of from 1-1,000 mg per kg body weight per day.

Claim #8

A method of treating or preventing poisoning in a mammal which is caused by circulation in the blood of said mammal of a poison selected from the group consisting of toxic metals, environmental toxins and mixtures thereof, comprising administering to a mammal in need of same an effective amount of modified pectin having a molecular weight of no more than 40,000 daltons, and obtained by hydrolysis or enzymatic degradation of pectin, in an amount to effectively bind said poison.

Claim #8 Dependents

The method of claim 8, wherein said poisoning is metal poisoning, and said poison is a poisonous heavy metal.

Claim #9 Dependents10

The method of claim 9, wherein said heavy metal is selected from the group consisting of aluminum, antimony, beryllium, bismuth, mercury, platinum, thallium, thorium, tin, tungsten, uranium, lead, mercury, cadmium, arsenic, silver, nickel, radioactive metals and mixtures thereof.

The method of claim 8, wherein said modified pectin is administered orally or intravenously.

Claim #11 Dependents12

The method of claim 11, wherein said modified pectin is administered orally in an amount of from 5-1,500 mg per kg body weight per day.

13The method of claim 11, wherein said modified pectin is administered intravenously in an amount of from 1-1,000 mg per kg body weight per day.

Claim #14

A method of treating or preventing arteriosclerosis caused by circulation of calcium in the blood of a mammal, comprising administering to said mammal modified alginate having a molecular weight of no more than 40,000 daltons, and obtained by hydrolysis or enzymatic degradation of alginic acid, in an amount to effectively bind said calcium.

Claim #14 Dependents15

The method of claim 14, wherein said amount is 2-15 grams of modified alginate per day.

Claim #16

A method of treating or preventing arteriosclerosis caused by circulation of calcium in the blood of a mammal, comprising administering to said mammal modified pectin having a molecular weight of no more than 40,000 daltons, and obtained by hydrolysis or enzymatic degradation of pectin, in an amount to effectively bind said calcium.

Claim #16 Dependents17

The method of claim 16, wherein said amount is 2-15 grams of modified pectin per day.